A plague has swept the world, and few people survive. One is Ren, a trapeze dancer/sex worker locked in quarantine at her strip club. The other is Ren's former teacher, Toby. Both spent years with the God's Gardeners, a cult focused on sustainable living that foresaw the plague, and so Ren and Toby are better prepared than most. As they wait out the last of the plague, Toby and Ren, each isolated from all other humans, think back on their lives. Atwood does a fantastic job of creating a dystopia that is both believable and slightly mad. Her characters feel real, with inner lives and unique personalities.
The one problem I had with this book is that it seems to be a companion to Oryx and Crake, which I never read, and Atwood's attempts to make this book fit with that one feel ham-handed.